2016 Jun;67(4):461-9. Taking flaxseed by mouth may help reduce. If you choose to use flax, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. J Am Coll Nutr 2010;29(1):72-80. Cancer Causes Control 2006;17:1253-61. Severe Interactions These medications are not usually taken together. Potent antihypertensive action of dietary flaxseed in hypertensive patients. Though tiny, they are rich in the omega-3 fatty acid ALA, lignans and fiber, all of which have been shown to have many potential health . These shiny seeds are packed with other nutrients, too,. However, when taken in large amounts and with too little water, flaxseed can cause: Avoid use of flaxseed and flaxseed oil during pregnancy. You may find that flaxseed oil leads to diarrhea. Information from this source is evidence-based and objective, and without commercial influence. Some medications that may interact with flaxseed oil negatively include: those that alter your blood flow and bleeding, including: aspirin blood thinners, like warfarin (Coumadin) and. Clin Cancer Res 2005;11:3828-35. Int J Cancer 2005;116:793-8. The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women. No, it's not always safe to take flaxseed oil with other medications. Role of Plant-Derived Omega-3 Fatty Acids in Human Nutrition. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Flaxseed can be used whole or crushed, or in a powder form as meal or flour. Am J Epidemiol 2007;165:514-23. Your body is an amazing physiological machine. Touillaud MS, Thiebaut AC, Fournier A, et al. 2013 May;33(5):367-75. Eur J Nutr. Flaxseed might lower blood pressure. This will help prevent any negative reactions that might arise. It is created by eHealthMe based on reports of 563 people who take Flaxseed and . Fish, walnuts, chia seeds and flaxseed oil are excellent sources of omega-3 fats. This content does not have an Arabic version. View abstract. Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts. You can find flaxseed oil in oil form, in capsules, or even in enriched food products. Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. 2016 Feb;25:90-5. Flax can affect blood-clotting and may increase your risk of bleeding. Clin Rheumatol. View abstract. View abstract. Flaxseed is a commonly recommended and used dietary supplement today. Our website services, content, and products are for informational purposes only. J Natl Cancer Inst 1993;85:1571-9. Though your body can make many types of fat on its own, such as cholesterol, omega-3 fatty acids are essential and must be supplied from outside sources. If we combine this information with your protected 2015 Apr;145(4):758-65. information highlighted below and resubmit the form. DOI: What are omega-3 fatty acids from fish oil? Hedelin M, Lof M, Olsson M, et al. Review/update the Flax is the seed of a plant called Linum usitatissimum, and is also known as Flax Seed, Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Flax, Echter Lein, Flachssamen, Flax Hull, Flax Lignans, Gemeiner Flachs, Graine de Lin, Kattan, Keten, Leinsamen, Lignans, Lin, Olagineux, Lin Textile, Linaza, Lini Semen, Linho, Lino, Linseed, Lint Bells, For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Most of the health benefits associated with omega-3 fatty acids from improving heart health to reducing inflammation are due to EPA and DHA, which come from fish and fish oil. This is not a complete list of side effects and others may occur. It's possible that taking flaxseed oil might increase the risk of bleeding. All rights reserved. Drug class: Herbal products. View abstract. Low adherence may be a contributing factor leading to uncontrolled blood pressure in patients. A total of 2 drugs are known to interact with Flax Seed Oil. Read more: 17 Reasons Why You Probably Need More Omega-3s in Your Diet. Dietary fiber and breast cancer. Sorry, we have no data available. Please contact your doctor or pharmacist. A total of 12 drugs are known to interact with green tea. Summary: Drug interactions are reported among people who take Flaxseed and Anastrozole. Atherosclerosis 1997;132:69-76. Int J Prev Med. It is also used for many other conditions, but there is no good. View abstract. Int J Cancer 2004;111:444-50.. View abstract. J Nutr 2008;138:938-45. Haggans CJ, Travelli EJ, Thomas W, et al. Eur J Clin Nutr 1998;52:749-53. Flaxseed interacts with 583 drugs . View abstract. Here are the seven side-effects of flaxseeds: 1. Fish oil may be a better and safer choice. Zeleniuch-Jacquotte A, Lundin E, Micheli A, et al. J Med Food 2012;15:840-5. Beta . View abstract. The phase IV clinical study analyzes what interactions people who take Flax seed and Aspirin have. The omega-3 supplement may increase your fasting blood sugar levels and decrease the effectiveness of your diabetes medication. Flaxseed: a potential treatment for lupus nephritis. View abstract. Stress: Stress, especially high levels of stress and anxiety, has been shown to lower and breakdown HRT at a quicker rate. Am J Clin Nutr 2004;79:318-25.. View abstract. Discuss with your doctor the benefits of flaxseed oil for your health before trying it out. Answer: Method 1 of 2:Taking Flaxseed Oil It is important to ask your doctor about adding flaxseed oil to your diet, especially if you are taking certain medications. View abstract. Sardines - bone loss, joint pain. Bloedon LT, Balikai S, Chittams J, et al. Use this medication regularly to get the most benefit from it. J Nutr 2006;136:3046-53. However, research has shown that flax may not be effective in treating this condition. Atherosclerosis 1998;136:367-75. Flax should not be used in place of medication prescribed for you by your doctor. According to Dr. Jaiswal, some of the common prescription and over-the-counter medications that interact with levothyroxine are: Antibiotics: ciprofloxacin, rifampin Seizure medications: phenytoin, fosphenytoin, and carbamazepine Antidepressants: amitriptyline, fluoxetine Consuming flaxseed oil may lower your blood pressure. View abstract. Schabath MB, Hernandez LM, Wu X, et al. An open-label study on the effect of flax seed powder (Linum usitatissimum) supplementation in the management of diabetes mellitus. Koizumi Y, Arai H, Nagase H, Kano S, Tachizawa N, Sagawa T, Yamaguchi M, Ohta K. [Case report: anaphylaxis caused by linseed included in baked bread]. View abstract. Last medically reviewed on September 26, 2017. Saw palmetto Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin Clopidogrel Warfarin St. John's wort 2005 - 2023 WebMD LLC. 2021;60(1):287-298. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Javidi A, Mozaffari-Khosravi H, Nadjarzadeh A, Dehghani A, Eftekhari MH. Sun J, Bai H, Ma J, et al. View abstract. J Am Coll Nutr 2001;20:143-8. View abstract. Hadi A, Askarpour M, Salamat S, Ghaedi E, Symonds ME, Miraghajani M. Effect of flaxseed supplementation on lipid profile: An updated systematic review and dose-response meta-analysis of sixty-two randomized controlled trials. View abstract. Flaxseed oil may cause complications with women who are pregnant because of its ability to affect hormones. This is one of the more common food-drug reactions. Morshedzadeh N, Shahrokh S, Aghdaei HA, et al. There is a chance you may have an allergy to flax seeds and flaxseed oil. View abstract. Eur J Clin Nutr. Before using flax, talk to your healthcare provider. You can learn more about how we ensure our content is accurate and current by reading our. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Dietary lignan intake and postmenopausal breast cancer risk by estrogen and progesterone receptor status. These types of drugs, herbs and supplements reduce blood clotting. Possible interactions include: . 4. 2019;10:218. View abstract. You should see your doctor immediately if you suspect youre having a reaction from the intake of flaxseed oil. View abstract. Flaxseed is packed with beneficial nutrients, omega-3 fatty acids, and fiber. Effects of dietary flaxseed in women with cyclical mastalgia. Yes: Flaxseed may interact with acetaminophen, certain antibiotics, estrogens, furosemide, Ketoprofen, diabetes medication, anticoagulants & Metoprolo. Diabetes drugs. Coulman KD, Liu Z, Michaelides J, et al. A prospective study of dietary fat and risk of prostate cancer. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 2016 Jun;35(3):615-25. Additionally, you may have to avoid the supplement completely. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. View abstract. Anticoagulant and anti-platelet drugs, herbs and supplements. Why Doesn't the U.S. Have at-Home Tests for the Flu? Flaxseed is high in soluble fiber and in lignans, which contain phytoestrogens. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 2013 Apr;16(4):357-60. Some people use black seed oil supplements to treat certain health conditions, including arthritis, allergies, asthma, and diabetes, and maintain a healthy weight. Wang L, Chen J, Thompson LU. Obstet Gynecol 2002;100:495-504.. View abstract. Natural Medicines. J Am Coll Nutr 2008;27:65-74. Can increase. But what you might not realize is that flaxseed contains very large amounts of lignans and phytoestrogens, making it one of the most estrogenic foods around. Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways. Khalesi S, Irwin C, Schubert M. Flaxseed consumption may reduce blood pressure: a systematic review and meta-analysis of controlled trials. The use of flax seeds or flaxseed oil may result in lowered blood sugar. J Clin Oncol 2007;25:648-55. J Steroid Biochem 1986;25:791-7.. View abstract. A phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes: North Central Cancer Treatment Group N08C7. National Center for Complementary and Integrative Health. Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients. There are 10 disease interactions with Cymbalta (duloxetine) which include: Liver Disease Renal Disease Depression Diabetes Glaucoma Hypertension Hyponatremia Mania Seizures Urinary Tract Obstruction Is it safe to eat raw flaxseed during pregnancy? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You should consume water regularly if you use flax seeds as a supplement. Flaxseed Mucilage (IQP-LU-104) Reduces Body Weight in Overweight and Moderately Obese Individuals in a 12-week, Three-arm, Double-blind, Randomized and Placebo-controlled Clinical Study. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. are using nonsteroidal anti-inflammatory drugs. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. View abstract. Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). There is a problem with You may be eager to find a supplement to boost the omega-3 fatty acids in your body. Determinants of serum enterolactone concentration. Learn about the medical uses, claims, and side effects of flaxseed. Flaxseed oil also might decrease blood clotting. Azrad M, Vollmer RT, Madden J, Dewhirst M, Polascik TJ, Snyder DC, Ruffin MT, Moul JW, Brenner DE, Demark-Wahnefried W. Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer. Flaxseed in lupus nephritis: a two-year nonplacebo-controlled crossover study. Flaxseed might also be helpful for managing diabetes and lowering the risk of heart disease. 2020:1-9. J Altern Complement Med 2020;26(9):799-806. Barre DE, et al. include protected health information. View abstract. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Freese R, Mutanen M. Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. However, it requires a steady dose of essential nutrients, which must come from food or supplements, in order to function at its best. Br J Nutr. Similar to any other medication, Trulicity (dulaglutide) may interact with certain drugs or health conditions. Goss PE, Li T, Theriault M, et al. Nutr Cancer 2007;58:162-70. When taken in recommended amounts, flaxseed and flaxseed oil are generally safe to use. View abstract. Though flaxseed oil benefits your blood pressure, if you take blood pressure medication and supplement your diet regularly with flaxseed oil, the combination may lower your blood pressure too much. Prasad K, Mantha SV, Muir AD, Westcott ND. Nutr J. J Natl Cancer Inst 1999;91:414-28. Research is strongly showing that long-term use of metformin and at high doses (1.5mg or higher daily) can deplete levels of vitamin B12. Common interactions include arthralgia among females and diarrhoea among males. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Meta-analysis of the effects of flaxseed interventions on blood lipids. Things to remember when you fill your prescription. Polypodium Leucotomos - Inotersen. JAMA 2005;294:1493-1504. those that regulate blood sugar, including. Learn how we can help 3.9k views Reviewed >2 years ago Thank Dr. John Munshower and 4 doctors agree 1 thank This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study. Comparisons of the effects of different flaxseed products consumption on lipid profiles, inflammatory cytokines and anthropometric indices in patients with dyslipidemia related diseases: systematic review and a dose-response meta-analysis of randomized controlled trials. For this reason, it is critical to discuss possible interactions with Trulicity before you start treatment with it. J Natl Cancer Inst 2007;99:475-86. Nordstrom DC, Honkanen VE, Nasu Y, et al. Flaxseed oil might lower blood pressure. Do not take this medication for more than 7 days unless directed by your doctor. A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk. Simbalista RL, Sauerbronn AV, Aldrighi JM, Areas JA. Chan School of Public Health: "Omega-3 Fatty Acids: An Essential Contribution", National Institutes of Health National Center for Complementary and Integrative Health: "Flaxseed and Flaxseed Oil", Harvard Health Publishing: "Why Not Flaxseed Oil? Kuijsten A, Arts IC, Hollman PC, et al. View abstract. Thompson LU, Rickard SE, Cheung F, et al. There is a high chance you may have an allergy to flaxseeds and flaxseeds oil. Do not take flax without medical advice if you are using any of the following medications: any medications for diabetes or high blood pressure; This list is not complete. View abstract. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Omega 3 dietary sources include flax seeds, chia seeds, walnuts, and fish. Crawford M, Galli C, Visioli F, et al. Eating flaxseed in muffins or other foods seems to increase, High cholesterol. 1. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in postmenopausal women. Ingredients: Stichopus Horrens Extract: Gamodulin Chlorella Vitamin E (dl-alpha-tocopherol) Flaxseed oil Direction Of Use: Adult 15ml each time, twice a day Twice a day preferably to be taken on empty stomach. Hypertension. View abstract. 2019;73(2):258-265. The present meta-analysis suggests that consumption of flaxseed may lower blood pressure slightly. Menopause 2006;13:631-42. Taking flaxseed along with diabetes medications might cause blood sugar to drop too low. Brouwer IA, Katan MB, Zock PL. Flax is often sold as an herbal supplement. Cancer Lett 2000;161:47-55. Flaxseed oil may be a good option for you. Vomiting and nausea may also be signs of an allergy. The adequate intake (AI) for omega-3 fatty acids is 1.6 grams for men and 1.1 grams for women. Sometimes flax seed will interfere with the absorption of other medications. Am J Clin Nutr 2001;73:1094-100. If you have a condition or take a medication that lowers your blood pressure, adding this supplement to your diet could cause complications. Aitken-Saavedra J, Chaves Tarquinio SB, De Oliveira da Rosa WL, et al. View abstract. One tablespoon of flaxseed oil has 7.26 grams. Lucas EA, Wild RD, Hammond LJ, et al. 2021;75(1):99-111. Moderate to vigorous physical activity, particularly aerobic exercise, has been shown to be associated with lower risk of bone fractures in women being treated with aromatase inhibitors. Clark WF, Parbtani A, Huff MW, et al. This might alter the effects of flaxseed. Effects of linseeds on the symptoms of irritable bowel syndrome: a pilot randomised controlled trial. Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice. This can increase the severity . Not all possible interactions are listed in this product guide. privacy practices. Alpha-linolenic acid in the treatment of rheumatoid arthritis. Journal of Nutrition. Cursed Get lost, blood pressure medication lawsuit change back to my little brat s appearance, or I won t be able to support you. View abstract. J Res Med Sci. The side effects of flaxseed oil may lead to adverse reactions if you consume it and take certain medications or have particular medical conditions. Ultimately, if flaxseed is to blame, an upped dosage of levothyroxine medication is probably needed going further. There is conflicting research about whether ALA found in flax seeds and flaxseed oil actually causes tumors from prostate cancer to be more aggressive. Asia Pac J Clin Nutr. To provide you with the most relevant and helpful information, and understand which Dodin S, Lemay A, Jacques H, et al. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. 2019;29:41-48. If you take insulin or other medication for diabetes, consult your physician before consuming flaxseed meal. Am J Clin Nutr 1999;69:395-402. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. Cancer Epidemiol Biomarkers Prev 2000;9:719-25. Flax seed oil is in the drug class herbal products. JAMA Pediatr. Chen J, Power KA, Mann J, et al. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Alvarez-Perea A, Alzate -Prez D, Doleo Maldonado A, Baeza ML. View abstract. Read about how you can use flaxseed oil . Suzuki R, Rylander-Rudqvist T, Saji S, et al. Do not use extra flax to make up the missed dose. Dietary phytoestrogen intake is associated with reduced colorectal cancer risk. Brand names: Flax Seed Oil, Flax Oil View abstract. View abstract. National Center for Complementary and Integrative Health. Talk to your primary care provider or pharmacist to discuss flaxseed oil drug interactions. View abstract. It may take 1 to 3 days before this medication starts working. The phase IV clinical study analyzes what interactions people who take Flaxseed and Metformin have. View abstract. View abstract. Can Apoaequorin Really Improve Your Memory? Adolescent dietary phytoestrogen intake and breast cancer risk (Canada). Taking flaxseed along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: A randomized trial. Nutr Cancer 1992;17:153-9. Flaxseed oil as a dietary supplement is not regulated by the U.S. Food and Drug Administration. 2015;145:758. Yari Z, Cheraghpour M, Alavian SM, Hedayati M, Eini-Zinab H, Hekmatdoost A. Do not use this product without medical advice if you are breast-feeding a baby. Phase II Trial of Flaxseed to Prevent Acute Complications After Chemoradiation for Lung Cancer. https://nccih.nih.gov/research/results/spotlight/062308.htm. Evaluation of the efficacy of flaxseed meal and flaxseed extract in reducing menopausal symptoms. Possible interactions include: Anticoagulant and anti-platelet drugs, herbs and supplements. Is Flaxseed Good for Thyroid? The most common medication used in women with PCOS is the insulin-sensitizer metformin. Read More Created for people with ongoing healthcare needs but benefits everyone. Accessed Sept. 27, 2017. In addition, 1.3 percent of patients who were unaware they had moderate kidney impairment took flaxseed oil, which translates to 167,500 Americans. Lewis JE, Nickell LA, Thompson LU, et al. View abstract. Eur J Clin Nutr. Dietary phytoestrogen intake--lignans and isoflavones--and breast cancer risk (Canada). Chen J, Power KA, Mann J, et al. those that alter your blood flow and bleeding, including: some nonsteroidal anti-inflammatory drugs, like ibuprofen and naproxen. Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. This may be problematic if you have a health condition that causes bleeding or if youre on certain medications that may lead to bleeding, such as blood thinners. Nutr J 2011;10:44. View abstract. Furthermore, some blood thinners, NSAID pain killers, hormone treatments, and certain medications for blood pressure, cholesterol, and diabetes may interact with flaxseed oil and flaxseed. Yes, several popular herbal supplements can impact the effectiveness of apixaban (Eliquis), rivaroxaban (Xarelto), betrixaban (Bevyxxa), and other anticoagulant drugs (blood-thinners) classified as direct factor Xa inhibitors. Summary: Drug interactions are reported among people who take Flaxseed and Metformin. Kidney Int 1995;48:475-80. Mandasescu S, Mocanu V, Dascalita AM, et al. Lemay A, Dodin S, Kadri N, et al. Giovannucci E, Rimm EB, Colditz GA, et al. J Clin Endocrinol Metab 2005;90:1390-7. Jenkins DJ, Kendall CW, Vidgen E, et al. Vitamin Keven in foods such as kale, lettuce, broccoli, and chickpeascan counteract a blood thinner's benefits. These medications are not usually taken together. Available for Android and iOS devices. View abstract. Clark WF, Kortas C, Heidenheim P, et al. This article explores 9 science-backed benefits of eating flaxseed. Leitzmann MF, Stampfer MJ, Michaud DS, et al. It is not certain whether flax is effective in treating any medical condition. Flaxseed is an herbal supplement used to treat constipation (chronic), enlarged prostate (oil), cancer (prevention), diabetes, diverticulitis, inflammation of the small intestine and/or the stomach, high cholesterol, irritable bowel syndrome, menopausal symptoms, myocardial infarction prevention (oil), skin inflammation, and systemic lupus View abstract. Cornish SM, Chilibeck PD, Paus-Jennsen L, et al. Appetite 2012;58:490-5. Click here for an email preview. Flaxseed - More Interactions. Rose DP. Copyright 1996-2023 Cerner Multum, Inc. Explore (NY) 2021. Do not give any herbal/health supplement to a child without medical advice. J Hum Nutr Diet 2012;25:435-43. information is beneficial, we may combine your email and website usage information with The effects of flaxseed dietary supplement on lipid profile, bone mineral density, and symptoms in menopausal women: a randomized, double-blind, wheat germ placebo-controlled clinical trial. Often youll need to take flaxseed oil a few hours before administering medications to make sure your body absorbs them properly. The effectiveness of your oral contraceptives or hormonal therapy may also be affected by flaxseed meal consumption. Am J Clin Nutr 1997;66:591-8. View abstract. Accessed Sept. 27, 2017. Mohammadi-Sartang M, Sohrabi Z, Barati-Bodaji R, Raeisi-Dehkordi H, Mazloom Z. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. Demark-Wahnefried W, Price DT, Polascik TJ, et al. Because flaxseed oil might decrease blood clotting, stop using flaxseed oil two weeks before having elective surgery. Chan School of Public Health. View abstract. Its important to be cautious when using flaxseed oil, as there are several risks and side effects. other information we have about you. Thanos J, Cotterchio M, Boucher BA, et al. Occasionally, using flaxseed or flaxseed oil causes an allergic reaction. The effect of flaxseed supplementation on body weight and ody composition: a systematic review and meta-analysis of 45 randomized placebo-controlled trials. These medications may cause some risk when taken together. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Common interactions include fatigue among females and drug ineffective among males. Haidari F, Banaei-Jahromi N, Zakerkish M, Ahmadi K. The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. Adlercreutz H, Fotsis T, Bannwart C, et al. Bongartz U, Hochmann U, Grube B, et al. Would you believe hundred grams of flaxseeds contain 813 mg of potassium. The Problem With Flaxseed And Thyroid Function. Int J Cancer 2006;119:925-31. Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study. Pharmacol Res. Milder IE, Feskens EJ, Arts IC, et al. Curr Probl Cardiol 2022;47(7):100931. Kuijsten A, Hollman PC, Boshuizen HC, et al. Do not use more of this product than is recommended on the label. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Thompson LU, Rickard SE, Orcheson LJ, Seidl MM. View abstract. Flaxseed can act like a laxative. If you need surgery, dental work, or a medical procedure, stop taking flax at least 2 weeks ahead of time. View abstract. Do not take this medication for more than 7 days unless directed by your doctor. Lampe JW, Martini MC, Kurzer MS, et al. J Allergy Clin Immunol 1996;98:469-70. Flaxseed might make these estrogen-containing drugs less effective. Cancer Causes Control 2000;11:679-85. Kolonel LN, Nomura AM, Cooney RV. Flaxseed reduces some risk factors of cardiovascular disease. Cancer Epidemiol Biomarkers Prev 2007;16:1364-70. Albuterol Inhalation (Ventolin) Amoxicillin (Amoxil) Azithromycin (Zithromax) CoQ10 (Coenzyme Q-10) Ibuprofen (Advil) Levothyroxine (Synthroid) Lexapro (Escitalopram) Lipitor (Atorvastatin) .