Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19. } ); Unfortunately, this is a much more rare blood type. Anderson's group examined data from Intermountain Healthcare, an integrated system of 24 hospitals and 215 clinics in Utah, Idaho, and Nevada. Case Rep Infect Dis. Pour en savoir plus sur la faon dont nous utilisons vos donnes personnelles, veuillez consulter notre politique relative la vie prive et notre politique en matire de cookies. The log2-transformed level of neutralizing antibodies was used as the independent variable. Of the 107,796 individuals tested for COVID-19, 11,468 patients tested positive. This narrative review was conducted to collect and discuss published data about neurological side effects of SARS-CoV-2 vaccines in order to discover type, frequency, treatment, and outcome of these side effects. (F) Comparison of adverse effects between individuals vaccinated with vaccines from the same and different manufacturers for the two doses. .css-13y9o4w{display:block;font-family:GraphikBold,GraphikBold-fallback,Helvetica,Arial,Sans-serif;font-weight:bold;margin-bottom:0;margin-top:0;-webkit-text-decoration:none;text-decoration:none;}@media (any-hover: hover){.css-13y9o4w:hover{color:link-hover;}}@media(max-width: 48rem){.css-13y9o4w{font-size:1.05rem;line-height:1.2;margin-bottom:0.25rem;}}@media(min-width: 40.625rem){.css-13y9o4w{font-size:1.28598rem;line-height:1.2;}}@media(min-width: 48rem){.css-13y9o4w{font-size:1.39461rem;line-height:1.2;margin-bottom:0.5rem;}}@media(min-width: 64rem){.css-13y9o4w{font-size:1.23488rem;line-height:1.3;}}This Coffee Shop Provides Free Therapy for Men, How To Stop Poop From Burning After Spicy Food, What to Do When You Hit Your Head Really Hard, 4 Things Every Man Should Know About Testosterone, The Truth About Testosterone and Your Libido, 20 Minutes of Exercise Lowers Hospitalization Risk. Reactogenicity analysis results are presented as percentage of participants. Wong LP, Alias H, Siaw YL, Muslimin M, Lai LL, Lin Y, et al. You will see significant upgrades in-store and online this year. An independent data-monitoring committee, comprising independent scientists not involved in this study, has been reviewing the data regularly for safety and scientific integrity. Diarrhea. Blood type is not associated with a severe worsening of symptoms in people who have tested positive for COVID-19, report Harvard Medical School researchers based at Massachusetts General Hospital. COVID vaccines and safety: what the research says. Immune cellular responses at 1240 days after the second dose of vaccine also supported the same manufacturers approach. NJ, BW, QiZ, and JZ analyzed the immune data of the participants. By February 21, 2021, more than 46 million persons received at least 1 dose of an mRNA-based COVID-19 vaccine. In addition, we are grateful to our colleagues Wenning Yang, Yafei Chu, Qiong Ma, and Wenbo Xu, who assisted with sample collection. We constantly strive to provide you with the best information possible. At intervals of 2 months, 8 mL of blood samples was collected from volunteers and distributed into four tubes (2 mL/tube) with or without the EDTA anticoagulant (two tubes for each) to detect neutralizing antibodies and cellular immune response parameters. You experience shortness of breath or swelling of the lips or face. Wong MCS, Wong ELY, Huang J, Cheung AWL, Law K, Chong MKC, et al. Serious side effects. This is why some vaccines require a brief observation period after your shot. The https:// ensures that you are connecting to the Third, because of limited resources, we could not perform pseudo-virus neutralization tests of neutralizing antibodies against COVID-19 (27). Follow-up visits were scheduled on days 130 to measure vital signs, review any solicited and unsolicited adverse events, and update medical and medication records. xhr.setRequestHeader('Content-Type', 'text/plain;charset=UTF-8'); doi:10.1016/S1473-3099(21)00479-5, 17. 2021;144(1):109110. If You Have One of These Blood Types, You May Be Safe From COVID, It Only Takes This Long to Get COVID in a Room With Someone Who Has It, These 2 Places Could Be Closing Soon, White House Official Warns, How Likely You Are to Catch COVID in the Next Month, Expert Says, If You Have This Symptom, There's an 80 Percent Chance You Have COVID, tracked the blood types of nearly 2,200 COVID-19 patients, A blood types were significantly more likely. Lancet (2022) 399:221225. These include anaphylaxis, a severe reaction . Would you like email updates of new search results? Front Public Health. Side effects after getting a #COVID19 vaccine are normal signs your body is building protection. We may earn a commission through links on our site. The original contributions presented in the study are included in the article/Supplementary Material. N Engl J Med (2020) 383:201829. -, Wiedmann M, Skattr T, StrayPedersen A, et al. Exacerbating GuillainBarr syndrome eight days after vectorbased COVID19 vaccination. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Doctors aren't yet sure if there is a link between the . Desmecht S, Tashkeev A, El MM, Marechal N, Pere H, Tokunaga Y, et al. doi:10.1128/spectrum.01181-21, 21. Source Reference: Anderson JL, et al "Association of Sociodemographic Factors and Blood Group Type With Risk of COVID-19 in a US Population" JAMA Netw Open 2021; DOI: 10.1001/jamanetworkopen.2021.7429. Unfortunately, to date, occupation- and blood type-disaggregated data on cellular and humoral immunogenicity have not been reported by studies on COVID-19 vaccines. Opens in a new tab or window, Visit us on YouTube. Safety of COVID-19 Vaccines Some people have no side effects. Less than 2% of the population have B negative blood. Co-authors disclosed support from Dell Loy Hansen Heart Foundation Heart Institute, Intermountain Research and Medical Foundation, AstraZeneca, PCORnet, GlaxoSmithKline, CareCentra, and LabMe.ai, as well as licensing of intellectual property from Alluceo and CareCentra. Those four main blood groupsA, AB, B, and Ocan be Rh-positive or Rh-negative, meaning that there are 8 blood groups in total. Many people have reported side effects, such as headache, fatigue, and soreness at the injection site, that are generally mild to moderate and go away within a few days. April 5, 2021. Blood clots with low platelets Capillary leak syndrome Guillain-Barr syndrome (GBS) Ongoing monitoring of side effects and reactions As the COVID-19 vaccine rollout continues across Canada, safety monitoring is ongoing. After the administration of the inactivated vaccine, the GMC of neutralizing antibodies decreased from 50.2 IU/mL on day 30 to 17.7 IU/mL (average decrease: 32.3%) and 13.3 IU/mL (average decrease: 25.9%) on days 180 and 240, respectively, representing an average monthly decrease of 10.1% (Figure2B). "There are two possibilities: You're Type O so you might not contract the virus because it has no landing stripthere's nothing to attach to," Dr. Udden explains. Unfolding the determinants of COVID-19 vaccine acceptance in China. Brand of vaccine administered (Moderna or Pfizer-BioNTech) and the change in average blood glucose, peak blood glucose, and percentage of time spent in normal range as well as above average range of blood glucose level following vaccine administration will be assessed. Along with its needed effects, sars-cov-2 (covid-19) mrna-1273 vaccine (the active ingredient contained in Moderna COVID-19 Vaccine) may cause some unwanted effects. doi:10.1016/j.vaccine.2022.02.065, 16. People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. All analyses, including linear regression, linear mixed models, and adverse effect analysis, were conducted using SPSS 25.0 (IBM Corporation, Armonk, NY, USA) and plotted using Prism 8.0. But both docs agree it shouldnt actually change anyones behavior. "Or by being Type O, the virus gets in but the A antibody prevents it from docking with enough cells to cause disease. Discussion: Two doses of the Chinese inactivated vaccine induced robust and rapid antibody expression and cellular immune responses. Molly Walker, Associate Editor, MedPage Today Yin F, Wu Z, Xia X, Ji M, Wang Y, Hu Z. What Your Blood Type Has to Do With Getting Covid, This Coffee Shop Provides Free Therapy for Men, Your Privacy Choices: Opt Out of Sale/Targeted Ads. (19, 20), we divided participants into three BMI groups: <18.5, 18.523.9, and >23.9 kg/cm2. Neurological autoimmune diseases following vaccinations against SARS-CoV-2: a case series. Front Neurol. All rights reserved. Either way, that would color how likely you are to not only get the virus but also how strong your symptoms are, he explains. We dont know why people with Type O might possibly be more protectedbut there are a lot of theories. Post SARS-CoV-2 vaccination Guillain-Barre syndrome in 19 patients. One study published by the CDC reports that from March 2020 to January 2021, patients with COVID-19 had nearly 16 times the risk for myocarditis compared with patients who did not have COVID-19. "Blood group O is significantly associated with reduced susceptibility to SARS-CoV-2. According to Pfizer, about 3.8% of their clinical trial participants experienced fatigue as a side effect and 2% got a headache. No use, distribution or reproduction is permitted which does not comply with these terms. afficher des publicits et des contenus personnaliss en fonction de vos profils de centres dintrt; mesurer lefficacit des publicits et contenus personnaliss; et. xhr.send(payload); Also, if possible, get some rest. An official website of the United States government. In conclusion, this study is the first to evaluate robust humoral and cellular immune responses at 240 days in 595 participants after a second dose of inactivated vaccine in individuals primed with the first dose. doi:10.1111/ane.13451 doi:10.1016/S0140-6736(22)00094-0, 7. YL, SW, and WY were involved in the project management and organizational work. Based on our research, we rate FALSE the claim that 1 million "COVID-vaccine injuries" are reported in a CDC database. Neutralizing antibody levels usually increase after the second administration of mixed vaccines (22, 23). In addition, people who are Black, who have died at a disproportionately high rate from Covid, tend to have higher levels of VWF, too. "Up to 10 percent of people who have COVID experience side effects such as . Environ Res (2022) 215:114131. doi:10.1016/j.envres.2022.114131, 3. Library job allowed him to plan the escape. The difference may be the type of antibodies we produce depending on blood type. Pain at the injection site, alongside redness and/or swelling Extended fatigue Headaches Widespread muscle pain Joint pain Chills Fever Nausea and vomiting According to current FDA publications,. Some research findings have suggested that people with blood types A and AB are more susceptible to contracting COVID-19,. The side effects mean your body is working hard to build the antibodies and cells it will need to fight the virus, if or when you are exposed to it. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). Safety definitions and a list of solicited adverse events were defined as previously described (16, 17). 1 The symptoms commonly reported were similar to those already associated with COVID-19 vaccines like fatigue, headache, and muscle pain. They also found non-white race, defined as African American, American Indian/Alaskan Native, Native Hawaiian, or Pacific Islander was associated with viral positivity (13.9% vs 6.9%, respectively) and hospitalization (23.9% vs 11.3%) versus white race. They looked at both how likely a patient was to contract COVID-19, and how likely they were to become seriously ill (or even die) from it if they did. There were no differences in the positive rate of neutralizing antibodies between the groups throughout the observation period (p = 0.891; Figure2A). Then, a study published in the New England Journal of Medicine confirmed the idea with a peer-reviewed study: Folks with Type A blood were 45 percent more likely to become infected with Covid than those with other blood types, while those with Type O were 35 percent less likely. Figure3 Quantitation of cell immune responses on days 1240 following administration of the Chinese inactivated vaccine. Bull Natl Res Cent. Common side effects included: tenderness at the injection site for 73% of participants pain upon and after vaccination for 60% of participants fatigue for 50% of the participants muscle pain. To control the COVID-19 epidemic and build an active immunization barrier among populations, the Chinese Government provided free COVID-19 vaccination to all citizens as of December 2020 (3). Si vous ne souhaitez pas que nos partenaires et nousmmes utilisions des cookies et vos donnes personnelles pour ces motifs supplmentaires, cliquez sur Refuser tout. But now, there's finally some good news for a third of Americans. Most side effects are mild and normally last only a day or two. Shaw AT, Bauer TM, de Marinis F, Felip E, Goto Y, Liu G, et al. In the case of the two mRNA COVID-19 vaccines, well over 90% of . Safety and reactogenicity of a liquid formulation of human rotavirus vaccine (porcine circovirus-free): A phase III, observer-blind, randomized, multi-country study. It may affect your immune systems strength or your inflammatory response to the infection. Factors that influence the concentration of neutralizing antibodies and cellular responses were analyzed using a multivariate linear regression model, which could be set on one of the classified variances as a reference to calculate the B value (18). mesurer votre utilisation de nos sites et applications. Epub 2021 May 25. -, Finsterer J, Scorza FA. However, this speculation requires validation using a larger patient cohort. Li JX, Wu SP, Guo XL, Tang R, Huang BY, Chen XQ, et al. Comment on "SARS-CoV-2 vaccinations may not only be complicated by GBS but also by distal small fiber neuropathy by J. Finsterer. Acceptance of the COVID-19 vaccine based on the health belief model: A population-based survey in Hong Kong. SARSCoV2 vaccines are not free of neurological side effects. Nous, Yahoo, faisons partie de la famille de marques Yahoo. Congestion/runny nose. The population required to be vaccinated included children aged 311 years, adolescents aged 1217 years, and adults. You'll always want to stay at your vaccination site for at least 15 minutes after you get the shot (30 minutes if you've had a severe allergic reaction before). Interestingly, individuals with blood type A produced lower amounts of IFN- at 180240 days after vaccination and had lower neutralizing antibodies at 114 days than those with blood type B. 2021;8(2021):3619131. doi:10.1155/2021/3619131 Typical side effects include pain at the injection site, fever, fatigue, headache, muscle pain, chills and diarrhoea. In fact, most people dont even know whether theyre Type A, B, AB, or O. Immunol. Domingo JL. Table4 Factors associated with CD4+ T-lymphocyte count after the administration of the Chinese inactivated COVID-19 vaccine. Yet these risks are relative, meaning people with type O blood are not immune to COVID-19. The first hint of a possible relationship came in March, from researchers in China, who compared nearly 2,200 hospitalized COVID-19 patients to a control group of approximately 27,000 healthy individuals. The concentration kinetics of IgG neutralizing antibodies were evaluated against the RBD for all study participants at least once during the 8-month timeframe and at least four times for 119 participants (20%). This can begin anywhere from a few minutes to a few hours after the injection. xhr.open('POST', 'https://www.google-analytics.com/collect', true); -, Finsterer J, Scorza FA, Scorca CA. Wang L, Fan JP, Xu Y, Wang JL, Wang MZ. All Rights Reserved. 2022 Galvanized Media. One, for instance, suggests that people with Type A may have a higher risk of catching Covid-19 and of. Use or keep moving your arm. Share on Facebook. Shes most passionate about hiking, traveling, mindfulness, cooking, and really, really good coffee. Lancet (2021) 398:12130. And for more on the state of the pandemic, check out These 2 Places Could Be Closing Soon, White House Official Warns. The profile of solicited adverse events in this study was consistent with that of a previous study (20). Kaulen LD, Doubrovinskaia S, Mooshage C, Jordan B, Purrucker J, Haubner C, Seliger C, Lorenz HM, Nagel S, Wildemann B, Bendszus M, Wick W, Schnenberger S. Eur J Neurol. PMC The full coverage rate of the COVID-19 vaccination program has reached approximately 90% of the population required to be vaccinated in 2022 (10). Front Immunol (2022) 13:863554. doi:10.3389/fimmu.2022.863554, 25. A few side effects are serious, but rare. Cytokine levels and lymphocyte subset counts were measured using flow cytometry (Beamcyte-1026; Changzhou Beamdiag Co., Ltd., Changzhou, China). Vaccines are still important, as are smart choices to protect yourself from germs. Blood type doesnt affect much in our daily lives. Opens in a new tab or window, Visit us on Facebook. In China, the latter three have been approved and are produced by eight manufacturers. Other neurological side effects occur in a much lower frequency. One of the most unusual and serious side-effects of the COVID-19 vaccine jab, which has been reported from various corners is Blood clotting. We also evaluated CD4+ T-lymphocyte counts, B-cell counts, and IFN- and IL-6 levels after stimulation with the S protein of SARS-CoV-2 in 543, 539, 513, and 512 individuals, respectively. O is the most common blood type in the U.S.: 37 percent of white Americans fall into this category, according to the American Red Cross, with the numbers rising to 47 percent among African-Americans, 53 percent among Latinx-Americans, and 39 percent of Asian-Americans. Lau YL, Fan Leung T, Sirvan Cetin B, Cagri Dinleyici E, Huang LM, Halperin SA, et al. Most participants rapidly developed neutralizing antibodies after two doses of the Chinese COVID-19 inactivated vaccine administered 3 weeks apart. Research in other countries has shown that the antibody titer of individuals vaccinated with a different type of vaccine 28 days after the first vaccination was higher than that of individuals vaccinated with a vaccine from the same manufacturer for both doses, without an increase in adverse reactions (14). Online ahead of print. The blood type-infection connection is not unique to the coronavirus. "Our next study will specifically look at such antibodies, and whether they explain the protective effect," Ray told Reuters. The most frequent of them are headache, GBS, VST, and transverse myelitis. This study had limitations. doi:10.1016/S0140-6736(22)00770-X, 26. We identified age as a contributing factor; with increasing age, the antibody concentration generated was decreased, and the rate of decrease in the neutralizing antibody concentration was rapid (age 3150 years vs. age 1830 years, B = 0.31, 95% CI 0.5 to 0.1; p = 0.009; Table2; Figure2C). If a patient was O-negative, they were particularly protected from the novel coronavirus, the authors noted. "The long-term side effects of COVID infection are a major concern," Goepfert said. dvelopper et amliorer nos produits et services. B negative red blood cells can be given to both B and AB patients. After adjusting for age, sex, occupation, blood type, interval between doses of vaccination, vaccination duration, and BMI, the highest geometric mean concentration (GMC) of neutralizing antibodies was 53.1 IU/mL in the same-manufacturer vaccination group at 1530 days, which was slightly but significantly higher than the 44.6 IU/mL found in the mixed-manufacturer vaccination group (p < 0.001) (Table2; Figure2B). The development of a vaccine that can overcome disadvantages including the stability of the materials used, limited immune response, and side effects, such as blood clotting, and provide a durable immune response will offer better protection from the deadly COVID-19 virus, the study said. This can be a sign of anaphylaxis, a severe allergic reaction. To analyze the changes in neutralizing antibodies and cellular immune responses over time, we used a mixed linear model with continuous natural log10-transformed cellular immune response data or the log2-transformed concentration of neutralizing antibodies against SARS-CoV-2 spike protein between days 1 and 240 as the dependent variable; age, sex, body mass index (BMI), occupation, vaccination mode, duration since the second dose, interval between doses of vaccination, and ABO blood were included as covariates in the models. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. To date, most of the Chinese population has been vaccinated with the inactivated vaccine. Nat Commun (2021) 12:1162. doi:10.1038/s41467-021-21444-5, 22. Lorsque vous utilisez nos sites et applications, nous utilisons des, authentifier les utilisateurs, appliquer des mesures de scurit, empcher les spams et les abus; et. These include: chills fatigue fever headache muscle pain nausea pain at the injection site redness at the. Treatment of these side effects is not at variance from similar conditions due to other causes. 30. The observations made in the "Study of blood group analysis and its correlation with lymphopenia in Covid- 19 infected people" were carried during the first wave of cases for two months in a retrospective manner. Opens in a new tab or window, Visit us on TikTok. Four types of COVID-19 vaccine have been approved for use worldwide: mRNA, inactivated virus, adenovirus, and recombinant protein vaccines (11). doi: 10.1016/S2213-2600(21)00220-4, 19. Other neurological side effects occur in a much lower frequency. In addition, a 2020 analysis in The Lancet found that compared to Covid patients who werent in intensive care, those who were critically ill in the ICU and died had higher VWF antigens in their blood. Acceptance of COVID-19 booster vaccination based on the protection motivation theory: A cross-sectional study in China. Vaccine (2022) 40:218490. Editorial: Rebound COVID-19 and cessation of antiviral treatment for SARS-CoV-2 with paxlovid and molnupiravir. J Med Internet Res (2021) 23:e26089. as it pertains to all aspects of your daily life. 2022 Nov 9;8(6):506-508. eCollection 2022 Dec 29. Kinetics and persistence of the cellular and humoral immune responses to BNT162b2 mRNA vaccine in SARS-CoV-2-naive and -experienced subjects: Impact of booster dose and breakthrough infections. Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6-17 years: A preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial. Even DNA testing company 23andMe tapped their customers and found that among 750,000 people who were diagnosed and hospitalized for Covid (this was prior to vaccines), those with type O were more protected. As of Dec. 24, there were more than 700,000 reports of adverse events . We are committed to bringing you researched, expert-driven content to help you make more informed decisions SARS-CoV-2 vaccinations may not only be complicated by GBS but also by distal small fibre neuropathy. Bruising for no. 2022 Dec 22;78:100157. doi: 10.1016/j.clinsp.2022.100157. Researchers have been talking about blood type and COVID-19 susceptibility for months. Opens in a new tab or window, Visit us on LinkedIn. The participants in the study (mixed-manufacturer vaccination for the two doses) and control (same-manufacturer vaccination for both doses) groups remained in local community health centers for at least 30min after vaccination to monitor safety, and the occurrence of any adverse event during this observation period was recorded. You've read a lot about what puts you at an increased risk of having a severe case of COVID-19, from smoking to carrying around extra weight to being over a certain age. Hum Vaccin Immunother (2022) 18:2078634. doi:10.1080/21645515.2022.2078634, 9. The relationships between blood type-, age-, sex-, and occupation-related reactivities of neutralizing antibodies and cellular immune responses were demonstrated. We may earn commission from links on this page, but we only recommend products we back. One study of over 3,000 people who got a COVID-19 vaccine did not find any increased side effects or other issues among people with different blood types. 36 COVID-19 vaccine recipients develop rare blood disorder after getting Moderna, Pfizer shots Immune thrombocytopenia is a condition that causes your platelet count to fall. Fatigue, headaches, muscle and joint aches and fever are all potential side effects as well. We know the Covid virus damages the lining of your blood vessels. O and Rh-negative blood types may already have COVID-19 antibodies. Neutralizing antibodies, interferon-gamma (IFN-), interleukin (IL)-6, CD4+ T-lymphocyte, and B-lymphocyte counts were evaluated in serum samples after stimulation with 2 g/mL SARS-CoV-2 spike protein for 16h at follow-up intervals of 2 months. While Anderson and colleagues noted their sample was mostly white, with a minority contribution from other ethnicities, they added their results were similar when restricted to white race alone. The virus can lead to pneumonia, respiratory failure, heart problems, liver problems, septic shock, and death. 2021;76:e3286. P=0.11), hospitalization (OR 0.89, 95% CI 0. . doi: 10.6061/clinics/2021/e3286. Bestlifeonline.com is part of the Meredith Health Group. Blood type is actually a pretty weak player, Dr. Udden says. The most commonly reported side effects were: Fever Headache Fatigue (tiredness) Pain at the injection site Helpful tips to relieve side effects Adults To relieve pain or swelling on the arm where you got the shot: Apply a clean, cool, wet washcloth over the area. doi:10.1001/jama.2021.19499, 11. The new study's co-author, Joel Ray, MD, of St. Michael's Hospital, suggested that people with these more resistant blood types may have already developed antibodies that can recognize certain aspects of the novel coronavirus and are therefore better prepared to fight it off. Women had 6.5 IU more neutralizing antibodies than men (B = 0.7, 95% CI 0.111.28; p = 0.021; least-square mean difference = 6.5, 95% CI 5.110.1, p = 0.019) 240 days after vaccination (Table S1). J Neuroimmunol. Methods: This prospective, multicenter, observational, longitudinal study involved 595 participants with a negative SARS-CoV-2 polymerase chain reaction result who were serologically tested and followed for 8 months after vaccination. Progress and challenge of COVID-19 vaccine development. } Furthermore, this study was the first to explore the association between the blood type of participants and humoral and cellular immune responses within 240 days after the administration of a Chinese inactivated vaccine. Whether the immunogenic response observed in this study will translate to better efficacy and effectivenessa fact that should be considered in strategic decisions about vaccination programsis unknown. Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: A randomised, open-label, single-centre trial. sharing sensitive information, make sure youre on a federal Immune responses to the heterologous vaccination schedule were within the range of those reported using homologous schedules. No. COVID-19 vaccine coverage, concerns, and preferences among Chinese ICU clinicians: A nationwide online survey. Borobia AM, Carcas AJ, Prez-Olmeda M, Castao L, Bertran MJ, Garca-Prez J, et al. Whether mild or severe, data from the U.S. Centers for Disease Control and Prevention (CDC), has shown that women are bearing the brunt of vaccine reactions, and experts believe it may be due to . BNT162b2 COVID-19 vaccine and correlates of humoral immune responses and dynamics: A prospective, single-centre, longitudinal cohort study in health-care workers.